Germ Out® Hand Antiseptic

The watermark in the background of this web site is an electron microscope picture of MRSA (methicillin resistant Staphylococcus aureus). Germ Out® kills MRSA on your hands in 15 to 30 seconds

Founder's Resume

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JOHN S. HIBBARD, Ph.D.

PRESIDENT, CEO of J & A COMPANIES, L.L.C.

●    Consultant - Microbiology / Pharmaceutical Research and                     Development

●    Manufacturer, Packager, Distributor and Sales of Germ Out®

4311 W. 112th Terrace                            Office: 913-530-1647

Leawood, Kansas                                    FAX:  913-661-0253 (please call before faxing)

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EXPERIENCE:

●    More than twenty years experience involving the clinical development and approval of drug products and medical devices.

●    More than thirteen years of graduate and postgraduate basic research in the fields of biochemistry, immunology, microbiology, molecular biology and pharmaceutical science.

●    Developed a network of highly qualified, nationally and internationally, respected investigators for clinical studies of drugs and medical devices.

●    Fifteen years experience teaching microbiology to graduate and second year medical school students.

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SYNOPSIS OF ACHIEVEMENTS:

●    Developed the following diagnostic tests and devices, Bac-T Screen®, Strep-ID®, CDT Test® ,ChloraPrep® One Step 3.0 mL. Applicator and Chlorascrub applicator.

●    Wrote and obtained NDA approval for the prescription drugs Carafate® Suspension, Rifater®, Valstar,  Chloraprep® and Chlorascrub, with an estimated combined sales of more than 455 million dollars per year.

●    Identified and developed a cost saving step in the CDT test which resulted in a savings of 35 million dollars over a 5 year period.

PROFESSIONAL CAREER:

J & A Companies, L.L.C. – Leawood, Kansas                  2000 to Present

PRESIDENT, CEO

●    Responsibilities included consulting for Pharmaceutical companies and Manufacture, Packaging, Distribution and Sale of the waterless hand sanitizer Germ Out®.

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BECKLOFF ASSOCIATES, INC. - Overland Park, Kansas        1997 to 2000

DIRECTOR OF CLINICAL AFFAIRS

●    Responsibilities include development and implementation of all clinical research projects from clinical operating plans to writing sections of NDAs.

STERISOURCE L.L.C. - Leawood, Kansas                     1995 to 1996

V.P. RESEARCH & DEVELOPMENT / OPERATIONS                                            

●    Responsibilities included all research, development, regulatory, labeling, packaging, and manufacturing  activities for the OTC antiseptic and disinfectant SEP-T-BAN.

CONSULTANT CLINICAL RESEARCH / MICOBIOLOGY  1994 to 1995        

Consulting for Strategem Inc., Water-Jel Technologies, and Pharmaceutical Formulations Inc.

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MARION LABORATORIES AND MARION MERRELL DOW INC. - Kansas City, Missouri

SENIOR CLINICAL RESEARCH SCIENTIST                               1992 - 1994

●    Clinical Research Department, Anti-Infectives/Oncology Section, Anti-mycobacterial Drugs

CLINICAL RESEARCH SCIENTIST                                             1988 - 1992

●    Clinical Research Department, General Medicine Section, Gastrointestinal Drugs

CLINICAL MICROBIOLOGIST                                                   1986 - 1988

CLINICAL MICROBIOLOGIST II                                                 1982 - 1986

●    Marion Laboratories, Department of Diagnostic Affairs

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ST. GEORGES UNIV. MED. SCHOOL - Grenada, WI                        1977 to 1984

UNIV. OF HEALTH SCIENCE- Kansas City, Missouri                        1972 to 1982

Department of Microbiology

DEPARTMENT HEAD AND ASSOCIATE PROFESSOR               1978 - 1982

ASSISTANT PROFESSOR                                                         1972 - 1978

OKLAHOMA STATE UNIVERSITY – Stillwater Oklahoma                     1971 to 1972

Department of Parasitology and Public Health at the College of Veterinary Medicine

ASSISTANT PROFESSOR

UNIVERSITY OF GEORGIA - Athens, Georgia                                      1969 to 1971

College of Veterinary Medicine

ASSISTANT PROFESSOR AND RESEARCH ASSOCIATE

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EDUCATIONAL BACKGROUND:

University of Kansas - Lawrence, Kansas

University of Kansas Medical Center - Kansas City, KS

Ph.D. in Microbiology, minor Biochemistry

BA in History and Zoology

 PROFESSIONAL SOCIETY MEMBERSHIPS:

American Society of Microbiology, Missouri Valley ASM, Kansas City ASM, American Society of Parasitology, American Society of Tropical Medicine and Hygiene, American Society for the Advancement of Science, The Lancefield Society, Drug Information Association

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PUBLICATIONS

1.     Hibbard, J. S., Field, M. F., and Mira, O. J. Fibrin Overlay Technique 64th Meeting American Society for Microbiology, Washington, D.C., V 87, 1964.

2.     Hibbard, J. S., Field, F. F., and Mira, O. J. Studies of a Fibrinolytic Enzyme from Primary Rhesus Monkey-Kidney Cells 66th Annual Meeting of the American Society for Microbiology, 54, V. 73, 1966.

3.     Hibbard, J. S. and Dusanic, D. G. Glucose and Endogenous Metabolism of Culture and Bloodstream Forms of Trypanosoma lewisi Proc 43rd Annual Meeting of the American Society of Parasitology, No. 40, p. 34, 1968.

4.     Hibbard, J. S. and Dusanic, D. G. Comparative Studies of Bloodstream and Culture Forms of Trypanosoma lewisi I. Oxygen Utilization, Carbon Dioxide Production and Glucose Uptake Comp. Biochem. and Physiol., 29, 621, 1969.

5.     Hibbard, J. S. and Dusanic, D. G. Comparative Studies of Bloodstream and Culture Forms of Trypanosoma lewisi II. Biochemical Composition Comp. Biochem. and Physiol., 32: 529-541, 1970.

6.     Hibbard, J. S. and Thompson, P. E. Chemotherapy of Filariasis Parasitic Diseases Panel - U.S. - Japan Cooperative Medical Science Program.  Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland, 1970.  Invited Participant.

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7.     Hibbard, J. S., Arnold, J. D. and Thompson, P. E. Scanning Electron Micrographs of the Filariid Litomosoides carinii Southern Society of Parasitologist Meeting, No. 16, Auburn University, March 18, 1971.

8.     Hibbard, J. S., Norred, C. J. and Thompson, P. E. Immunizing Agents of the Filarial Parasite Litomosoides carinii Southern Society of Parasitology Meetings, No. 25, Auburn University, March 18, 1971.

9.     Hibbard, J. S., Norred, C. J. and Thompson, P. E. Artificially Acquired Immunity to Litomosoides carinii Microfilaria in the Mongolian Jird Joint Conference on Filariasis and Schistosomiasis.  U. S. - Japan Cooperative Medical Science Program, Geographic Medicine Branch, NIAID, NIH, July 26-28, 1971.  Invited Participant.

10.   Hibbard, J. S., Zeigler, J. B. and Thompson, P. E. Chemotherapy of Litomosoides carinii Joint conference of Filariasis and Schistosomiasis.  U. S. - Japan Cooperative Medical Science Program Geographic Medicine Branch, NIAID, NIH, July 26-28, 1971.  Invited Participant.

11.   Pezzlo, M. T., Hibbard, J. S. and Matsen, J. M. Monograph:  Screening for Urinary Tract Infections Marion Scientific, A Division of Marion Laboratories Inc. Kansas City, Missouri 64114.  February 1984.

12.   Hibbard, J. S. Clostridium difficile - Associated Colitis and Pseudomembranous Colitis Am.J.Clin.Prod.Rev., Feb: 18-23, 1986.

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13.   Hibbard, J. S. Carafate Suspension New Drug Application (NDA) - Clinical Section (8), Overall Summary of Controlled and Uncontrolled Studies, Integrated Summaries of Effectiveness, Safety, and Benefits and Risks, Labeling and Application Summary.  NDA submitted to the FDA in 1989 and approved in 1993.

14.   Hibbard, J. S. Rifater New Drug Application (NDA) Created a database and listings for one of the controlled studies in the NDA, wrote the entire Clinical Section (8) including the clinical study reports, the Overall Summary of Controlled and Uncontrolled Studies, the Integrated Summaries of Effectiveness, Safety and the Benefits and Risks, Labeling and Application Summary.  NDA submitted to the FDA on May 19, 1993 and approved on June 2, 1994.

15.   Hibbard, J.S. Rifapentine New Drug Application Directed strategy for drug development and approval in the U.S. Wrote protocols and initiated phase II clinical trials  for Rifapentine in South Africa and the United States. Rifapentine NDA was filed in 1997 and approved in 1998.

16.   Hibbard J.S. Valstar (valrubicin) New Drug Application Wrote the Human Pharmacokinetic and Bioavailability section of the NDA including the summary section 2.6, all of section 6.0, and the PK section of the labeling. Valstar NDA was filed and approved in 1999.

17.   Hibbard J.S. 2% Chloraprep New Drug Application. Project Director for drug development in the U.S. Wrote  protocols for two pivotal clinical studies. Monitored both studies from prestudy site visits to closing site visits. Reviewed and commented on the Clinical Statistical Reports. The Clinical Statistical reports were filed as an amendment to the NDA on January 13, 2000 and the NDA was approved in July of 2000.

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18.     John S. Hibbard, Gayle K. Mulberry, and Ann R. Brady. ChloraPrep Compared with Isopropyl Alcohol or Aqueous Chlorhexidine for Skin Antisepsis. At Poster Presentation No. 9 on Tuesday May 1, 2001 and at Oral Presentation No. 4 on Wednesday May 2, 2001 at the 2001 Intravenous Nurses Society Annual Meeting and Industrial Exhibit in Indianapolis, Indiana.

 19.  Robert Garcia, John S. Hibbard. Antimicrobial Activity of a Recently Approved Chlorhexidine-Isopropyl Alcohol Antiseptic vs 70% Isopropyl Alcohol: A Randomized, Blinded Trial. An Oral Presentation at the 28th Annual Educational Conference and International Meeting of the Association for Professionals in Infection Control and Epidemiology. June 12, 2001 at 2:30 PM in Seattle, Washington.

 20.  John S. Hibbard. Administration of 2% Chlorhexidine Gluconate in 70% Isopropyl Alcohol Is Effective in 30 Seconds. Letter to the Editor. Infection Control and Hospital Epidemiology, May, 23 No.5: 233, 2002

 21.  John S. Hibbard, Gayle K. Mulberry, Ann R. Brady. A Clinical Study Comparing the Skin Antisepsis and Safety of ChloraPrep, 70% Isopropyl Alcohol, and 2% Aqueous Chlorhexidine. Journal of Infusion Nursing, July-August, 25 No.4: 244-249, 2002

 22.  Robert Garcia, Gayle Mulberry, Ann Brady, and John S. Hibbard. Comparison of ChloraPrep and Betadine as Preoperative Skin Preparation Antiseptics. A Poster Presentation at the 40th Annual Meeting of the Infectious Disease Society of America, October 25, 2002.

23.  Hibbard, J.S. 3.15% Chlorascrub New Drug Application (NDA). Project consultant for drug development in the U.S. Reviewed and commented on protocols for two pivotal clinical studies. Consulted on both studies from pre-study site visits to closing site visits. Reviewed and commented on the Clinical Statistical Reports. Wrote and prepared sections 7, 8, 9, 10, 11, and 12 and reviewed and commented on sections 2, 3, 5 and 6 of the NDA. The NDA was filed in 2004 and approved by the FDA in 2005.

24.   John S. Hibbard. Comparative Analysis of the Antimicrobial Activity and Safety of Current Antiseptic Agents. An Oral Presentation at the Infusion Nurses Society, National Academy of Infusion Therapy meeting, Session Code 001, May 1, 2004, Salt Lake City, Utah.

25.   John S. Hibbard. Analyses Comparing the Antimicrobial Activity and Safety of Current Antiseptic Agents: A Review. Journal of Infusion Nursing, May-June, 28 No.3: 194-207, 2005

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26.   John S. Hibbard. Initial Treatment of Infectious Diseases: One or Two Antimicrobials. Microbe, Vol. 1 No. 5: 209, 2006.

27.   John S. Hibbard. Combined Antimicrobial Treatment of Infectious Diseases. Microbe, Vol. 1 No. 12: 549, 2006.

28.   John S. Hibbard. Combined Antimicrobial Therapy - Can We Outsmart the Microbes? Microbe, Vol. 2 No. 6: 271, 2007.

29.   John S. Hibbard. Combination Antimicrobial Treatment – Benefits and Risks. Microbe, Vol. 3 No. 1: 2, 2008.

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Mailing Address:4311 W. 112th Terrace, Leawood, Kansas 66211

                                                                                                                                                                                                                         E-Mail Address: johnshibbard@att.net                                                                                                                                                        

Telephone 913-530-1647, Facsimile 913-661-0253 (please call before faxing)

Copyright © 2005 J & A Companies, L.L.C.